BRCC3 抗体 (AA 266-316)
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Quick Overview for BRCC3 抗体 (AA 266-316) (ABIN7448440)
抗原
See all BRCC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 266-316
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原理
- Rabbit anti-BRCC36 IHC Antibody, Affinity Purified
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预测反应
- Mouse,Horse,Pig,Panda,Orangutan,Monkey,White-tufted-ear marmoset,Dusky titi monkey,Nine-banded armadillo,Crab-eating macaque,Little brown bat,African elephant,Northern white-cheeked gibbon,Greater horseshoe bat
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纯化方法
- Affinity Purified
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免疫原
- Between AA 266 and 316
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亚型
- IgG
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anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 14-316) antibody
BRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316), (N-Term) antibodyBRCC3 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) antibodyBRCC3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1580 unconjugated Recombinant Antibody
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 36-70) antibodyBRCC3 适用: 人 WB 宿主: 兔 Polyclonal RB54401 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 18-50) antibodyBRCC3 适用: 人 WB 宿主: 兔 Polyclonal RB53911 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) antibody (FITC)BRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
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别名
- BRCC36
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背景
- Background: BRCA1/BRCA2-containing complex subunit 36 (BRCC36) is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. BRCC36 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, BRCC36 specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs) [taken from the Universal Protein Resource (UniProt) P46736].
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基因ID
- 79184
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NCBI登录号
- NP_077308
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UniProt
- P46736
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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