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GDF5 抗体 (AA 201-300)

This anti-GDF5 antibody (ABIN718376) is a Rabbit Polyclonal antibody detecting GDF5 in WB, ELISA. Suitable for Human, Mouse.
产品编号 ABIN718376
发货至: 中国

Quick Overview for GDF5 抗体 (AA 201-300) (ABIN718376)

抗原

See all GDF5 抗体
GDF5 (Growth Differentiation Factor 5 (GDF5))

适用

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  • 41
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人, 小鼠

宿主

  • 89
  • 5
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  • 3
  • 1

克隆类型

  • 93
  • 8
多克隆

标记

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  • 1
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This GDF5 antibody is un-conjugated

应用范围

  • 75
  • 47
  • 34
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  • 9
  • 9
  • 5
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Western Blotting (WB), ELISA
  • 抗原表位

    • 11
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
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    AA 201-300

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CDMP1/GDF5

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GDF5 (Growth Differentiation Factor 5 (GDF5))

    别名

    CDMP1

    背景

    Synonyms: Cartilage derived morphogenetic protein 1, Cartilage-derived morphogenetic protein 1, CDMP-1, CDMP1, GDF-5, Gdf 5, GDF5_HUMAN, Growth dferentiation factor 5, Growth/dferentiation factor 5, LAP4, Radotermin.

    Background: Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.

    基因ID

    8200
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