Recombinant IL5 (Mepolizumab Biosimilar) 抗体
Research Grade
适用: 人
ELISA
宿主: Mammalian Cells
Monoclonal
unconjugated
Recombinant Antibody
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- 抗原
- IL5 (Mepolizumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
- 宿主
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Mammalian Cells
- Expression System
- Mammalian cells
- 克隆类型
- 单克隆
- 应用范围
- ELISA
- 原理
- Mepolizumab Biosimilar - Anti-IL5 mAb
- 产品特性
- Antibody Type: IgG1-kappa
- 纯化方法
- Recombinant antibody expressed in mammalien cells and purified.
- 质量等级
- Research Grade
- 亚型
- IgG1 kappa
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- 限制
- 仅限研究用
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- 缓冲液
- PBS pH 7.5
- 储存条件
- -80 °C
- 储存方法
- store at -80°C
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- 抗原
- IL5 (Mepolizumab Biosimilar)
- 物质类
- Biosimilar
- 背景
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SB-240563
Mepolizumab is a fully humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells. (EGPA) and eosinophilia syndrome (HES). The pathogenesis of eosinophils is complex, but IL-5 is considered a key eosinophilic factor, involved in the differentiation, recruitment, activation and prolonged survival of eosinophils in peripheral tissues. Activated eosinophils further stimulate the inflammatory response, and also induce tissue damage and promote fibrosis, all of which contribute to the multifactorial symptoms of eosinophilic disease. Mepolizumab is used to treat severe asthma. - CAS-编号
- 196078-29-2
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