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K63-Linked Polyubiquitin 抗体

The 兔 单克隆 anti-K63-Linked Polyubiquitin antibody is suitable to detect K63-Linked Polyubiquitin in samples from 人. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN7384503
发货至: 中国
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Quick Overview for K63-Linked Polyubiquitin 抗体 (ABIN7384503)

抗原

K63-Linked Polyubiquitin

适用

  • 11
  • 9
  • 9

宿主

  • 9
  • 2

克隆类型

  • 11
单克隆

标记

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

R06-2H7
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    K63-Linked Polyubiquitin

    别名

    Ubiquitin K63

    背景

    UBB,UBB,Ubiquitin,This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. 

    分子量

    Observed_MW: 8kDa

    Calculated_MW: 8kDa

    基因ID

    7314

    UniProt

    P0CG47
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