C-AMP Protein Kinase (Catalytic Subunit) 抗体
This 兔 单克隆 antibody specifically detects C-AMP Protein Kinase in WB, IP, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7384424
发货至:
中国
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Quick Overview for C-AMP Protein Kinase (Catalytic Subunit) 抗体 (ABIN7384424)
抗原
C-AMP Protein Kinase
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
R07-8H3
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抗原表位
- Catalytic Subunit
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纯化方法
- Affinity Purified
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亚型
- IgG
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anti-C-AMP Protein Kinase (Catalytic Subunit) antibody
KD Validated 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1030 unconjugated Recombinant Antibody
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应用备注
- WB 1:1000-1:2000 IHC 1:50-1:100 IF 1:50-1:100
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限制
- 仅限研究用
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浓度
- 300 μg/mL
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缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- C-AMP Protein Kinase
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别名
- cAMP Protein Kinase
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背景
- CAMP dependent protein kinase alpha catalytic subunit,cAMP dependent protein kinase beta catalytic subunit,cAMP dependent protein kinase catalytic beta subunit isoform 4ab,cAMP dependent protein kinase catalytic subunit alpha,cAMP dependent protein kinase catalytic subunit alpha,isoform 1,cAMP dependent protein kinase catalytic subunit beta,cAMP-dependent protein kinase catalytic subunit alpha,KAPCA,PKA C alpha,PKA C beta,PKA C-alpha,PKACA,PKACB,PPNAD4,PRKACA,PRKACAA,PRKACB,Protein kinase A catalytic subunit alpha,Protein kinase A catalytic subunit,Protein kinase A catalytic subunit beta,Protein kinase cAMP dependent catalytic alpha,Protein kinase cAMP dependent catalytic beta,This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.
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分子量
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Observed_MW: 41kDa
Calculated_MW: 41kDa
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基因ID
- 5566
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UniProt
- P17612
抗原
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