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BCR 抗体

This anti-BCR antibody is a 兔 单克隆 antibody detecting BCR in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7384420
发货至: 中国

Quick Overview for BCR 抗体 (ABIN7384420)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

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宿主

  • 93
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克隆类型

  • 97
  • 4
单克隆

标记

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  • 1
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This BCR antibody is un-conjugated

应用范围

  • 72
  • 38
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

R02-6I0
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000 IHC 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    Bcr

    背景

    ALL,bcr,BCR1,Breakpoint cluster region,CML,D22S11,D22S662,PHL,Renal carcinoma antigen NY-REN-26,A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 160kDa

    Calculated_MW: 143kDa

    基因ID

    613

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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