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YTHDF1 抗体

This anti-YTHDF1 antibody is a 兔 单克隆 antibody detecting YTHDF1 in WB. Suitable for 人 和 Hamster.
产品编号 ABIN7384402
发货至: 中国

Quick Overview for YTHDF1 抗体 (ABIN7384402)

抗原

YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

适用

  • 22
  • 10
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, Hamster

宿主

  • 24

克隆类型

  • 21
  • 3
单克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This YTHDF1 antibody is un-conjugated

应用范围

  • 15
  • 9
  • 5
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

R05-2E7
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

    别名

    YTHDF1

    背景

    C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.

    分子量

    Observed_MW: 61kDa

    Calculated_MW: 61kDa

    基因ID

    54915

    UniProt

    P59326
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