Interleukin enhancer-binding factor 3 (ILF3) 抗体
Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) 抗体 (ABIN7384360)
抗原
See all Interleukin enhancer-binding factor 3 (ILF3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Purified
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亚型
- IgG
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应用备注
- WB 1:2000-1:5000 IHC 1:50-1:100 IF 1:50-1:100
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限制
- 仅限研究用
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浓度
- 300 μg/mL
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缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Interleukin enhancer-binding factor 3 (ILF3)
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别名
- ILF3
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背景
- CBTF,Double stranded RNA binding protein 76,Double-stranded RNA-binding protein 76,DRBF,DRBP76,ILF3,ILF3,Interleukin enhancer binding factor 3,Interleukin enhancer-binding factor 3,M phase phosphoprotein 4,M-phase phosphoprotein 4,MPHOSPH4,MPP4,NF AT 90,NF-AT-90,NF110,NF90,NFAR,Nuclear factor associated with dsRNA,Nuclear factor of activated T cells 90 kDa,Nuclear factor of activated T-cells 90 kDa,TCP80,Translational control protein 80,This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
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Observed_MW: 95kDa
Calculated_MW: 95kDa
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基因ID
- 3609
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UniProt
- Q12906
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途径
- M Phase
抗原
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