Lactate Dehydrogenase A 抗体
Quick Overview for Lactate Dehydrogenase A 抗体 (ABIN7384336)
抗原
See all Lactate Dehydrogenase A (LDHA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Affinity Purified
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亚型
 - IgG
 
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应用备注
 - WB 1:1000-1:2000
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限制
 - 仅限研究用
 
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浓度
 - 300 μg/mL
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缓冲液
 - 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- Lactate Dehydrogenase A (LDHA)
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别名
 - Lactate Dehydrogenase A
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背景
 - Cell proliferation-inducing gene 19 protein,GSD11,L lactate dehydrogenase A chain,l7R2,LDH M,LDH muscle subunit,LDH1,PIG19 Proliferation-inducing gene 19,LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
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分子量
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Observed_MW: 37kDa
Calculated_MW: 37kDa
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基因ID
 - 3939
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UniProt
 - P00338
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途径
 - Warburg Effect
 
抗原
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