EEF1E1 抗体
Quick Overview for EEF1E1 抗体 (ABIN7384097)
抗原
See all EEF1E1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human EEF1E1 (NP_004271.1).
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亚型
- IgG
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应用备注
- WB 1:200-1:2000 IF 1:50-1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
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别名
- EEF1E1
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背景
- EEF1E1,AIMP3,P18,This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
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分子量
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Observed_MW: 20 kDa
Calculated_MW: 15 kDa/19 kDa
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基因ID
- 9521
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UniProt
- O43324
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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