AGXT 抗体
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北京 101111
Quick Overview for AGXT 抗体 (ABIN7384024)
抗原
See all AGXT 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human AGXT
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亚型
- IgG
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- AGXT (Alanine Glyoxylate Aminotransferase (AGXT))
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别名
- AGXT
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背景
- AGT,AGT1,Agxt,AGXT1,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminotransferase,L alanine glyoxylate aminotransferase 1,MS773,PH1,Serine pyruvate aminotransferase,Serine--pyruvate aminotransferase,Serine--pyruvate aminotransferase,mitochondrial,Serine:pyruvate aminotransferase,SPAT,SPT,SPYA,TLH6,Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
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分子量
- 43 kDa
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NCBI登录号
- NP_000021
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UniProt
- P21549
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途径
- Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport
抗原
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