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AGXT 抗体

This anti-AGXT antibody is a 兔 多克隆 antibody detecting AGXT in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7384024
发货至: 中国

Quick Overview for AGXT 抗体 (ABIN7384024)

抗原

See all AGXT 抗体
AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

适用

人, 小鼠, 大鼠

宿主

  • 37
  • 7
  • 2

克隆类型

  • 39
  • 7
多克隆

标记

  • 27
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AGXT antibody is un-conjugated

应用范围

  • 26
  • 21
  • 18
  • 12
  • 9
  • 7
  • 6
  • 3
  • 2
Western Blotting (WB), ELISA
  • 纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human AGXT

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

    别名

    AGXT

    背景

    AGT,AGT1,Agxt,AGXT1,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminotransferase,L alanine glyoxylate aminotransferase 1,MS773,PH1,Serine pyruvate aminotransferase,Serine--pyruvate aminotransferase,Serine--pyruvate aminotransferase,mitochondrial,Serine:pyruvate aminotransferase,SPAT,SPT,SPYA,TLH6,Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

    分子量

    43 kDa

    NCBI登录号

    NP_000021

    UniProt

    P21549

    途径

    Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport
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