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PAX5 抗体

This anti-PAX5 antibody is a 兔 多克隆 antibody detecting PAX5 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7383990
发货至: 中国

Quick Overview for PAX5 抗体 (ABIN7383990)

抗原

See all PAX5 抗体
PAX5 (Paired Box 5 (PAX5))

适用

  • 167
  • 53
  • 10
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  • 2
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  • 2
  • 1
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人, 小鼠

宿主

  • 85
  • 77
  • 5
  • 1

克隆类型

  • 94
  • 74
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This PAX5 antibody is un-conjugated

应用范围

  • 85
  • 45
  • 39
  • 16
  • 15
  • 14
  • 13
  • 10
  • 10
  • 8
  • 4
  • 4
  • 4
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  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human PAX5

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PAX5 (Paired Box 5 (PAX5))

    别名

    PAX5

    背景

    B cell lineage specific activator,B cell lineage specific activator protein,B cell specific activator protein,B cell specific transcription factor,B-cell-specific transcription factor,BSAP,EBB-1,KLP,Paired box 5,Paired box gene 5 (B cell lineage specific activator protein),Paired box gene 5 (B cell lineage specific activator),Paired box gene 5,Paired box homeotic gene 5,Paired box protein Pax 5,Paired box protein Pax-5,Paired domain gene 5,PAX 5,PAX5,PAX5,Transcription factor PAX 5,This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

    分子量

    42 kDa

    NCBI登录号

    NP_057953

    UniProt

    Q02548
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