ZIKV E
适用: Virus
ELISA
宿主: 小鼠
Monoclonal
ID5
unconjugated
应用备注
WB 1:1000-1:5000 ELISA 1:1000-1:2000
限制
仅限研究用
浓度
1 mg/mL
缓冲液
0.2 μm filtered solution in PBS
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
ZIKV E
(Zika Virus Envelope (ZIKV E))
别名
ZIKV Envelope Protein
背景
E,Envelope Protein,Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76 % of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.