SARS-CoV N
适用: Coronavirus (CoV)
ELISA, WB, IF
宿主: 小鼠
Monoclonal
1516583
unconjugated
应用备注
WB 1:1000-1:5000 ELISA 1:5000-1:10000
限制
仅限研究用
浓度
1 mg/mL
缓冲液
0.2 μm filtered solution in PBS
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
别名
SARS-CoV Nucleoprotein / NP
背景
Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus NP,novel coronavirus Nucleocapsid,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.