SARS-CoV-2 Spike S2 抗体
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Quick Overview for SARS-CoV-2 Spike S2 抗体 (ABIN7383760)
抗原
See all SARS-CoV-2 Spike S2 (SARS-CoV-2 S2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- SARS-COV-2 Spike S2 Monoclonal Antibody(2019-nCoV)
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纯化方法
- Antigen affinity purification
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免疫原
- Recombinant 2019-nCoV S2 Protein (ECD, His Tag),PKSR030505
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亚型
- IgG1
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anti-SARS-CoV-2 Spike S2 (SARS-CoV-2 S2) antibody
SARS-CoV-2 S2 适用: SARS Coronavirus-2 (SARS-CoV-2) WB, IF 宿主: 兔 Monoclonal unconjugated
anti-SARS-CoV-2 Spike S2 (SARS-CoV-2 S2) antibodySARS-CoV-2 S2 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: 兔 Monoclonal DM25 unconjugated
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应用备注
- ELISA: 1:5,000-1:10,000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 0.2 μm filtered solution in PBS
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SARS-CoV-2 Spike S2 (SARS-CoV-2 S2)
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别名
- SARS-COV-2 Spike S2
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物质类
- Viral Protein
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背景
- Coronavirus s2,coronavirus spike,cov spike,ncov,ncov s2,ncov spike,novel coronavirus s2,novel coronavirus spike,s2,Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
抗原
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