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SARS-CoV-2 Spike 抗体 (RBD)

This anti-SARS-CoV-2 Spike antibody is a Human 单克隆 antibody detecting SARS-CoV-2 Spike in ELISA. Suitable for SARS Coronavirus-2 (SARS-CoV-2).
产品编号 ABIN7383759
发货至: 中国

Quick Overview for SARS-CoV-2 Spike 抗体 (RBD) (ABIN7383759)

抗原

See all SARS-CoV-2 Spike 抗体
SARS-CoV-2 Spike

适用

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SARS Coronavirus-2 (SARS-CoV-2)

宿主

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Human

克隆类型

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单克隆

标记

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This SARS-CoV-2 Spike antibody is un-conjugated

应用范围

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ELISA

克隆位点

5-00E-008
  • 抗原表位

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    RBD

    特异性

    SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)

    纯化方法

    Antigen affinity purification

    免疫原

    Recombinant 2019-nCoV S Protein RBD-SD1 (C-6His),PKSR030477

    亚型

    IgG1
  • 应用备注

    ELISA: 1:5,000-1:10,000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.2 μm filtered solution in PBS

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SARS-CoV-2 Spike

    物质类

    Viral Protein

    背景

    Coronavirus s1,coronavirus s2,coronavirus spike,cov spike,ncov RBD,ncov s1,ncov s2,ncov spike,novel coronavirus RBD,novel coronavirus s1,novel coronavirus s2,novel coronavirus spike,RBD,S1,s2,Spike RBD,Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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