SARS-CoV-2 NSP1 抗体
The 山羊 多克隆 anti-SARS-CoV-2 NSP1 antibody is suitable to detect SARS-CoV-2 NSP1 in samples from SARS Coronavirus-2 (SARS-CoV-2). It has been validated for WB.
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产品编号 ABIN7272996
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for SARS-CoV-2 NSP1 抗体 (ABIN7272996)
抗原
SARS-CoV-2 NSP1
(SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))
适用
SARS Coronavirus-2 (SARS-CoV-2)
宿主
山羊
克隆类型
多克隆
标记
This SARS-CoV-2 NSP1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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原理
- anti-NSP1 (SARS-CoV-2)
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序列
- MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG
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特异性
- In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot.
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交叉反应 （详细）
- Reacts with SARS-CoV-2 protein
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纯化方法
- Epitope affinity purified
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免疫原
- Affinity purified recombinant fusion protein Nsp1 of SARS-CoV-2 produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:500-1:2,000
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限制
- 仅限研究用
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浓度
- 3 mg/mL
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缓冲液
- PBS, 20 % glycerol and 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- SARS-CoV-2 NSP1 (SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))
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别名
- NSP1 (SARS-CoV-2)
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物质类
- Viral Protein
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背景
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Host translation inhibitor Nsp1 is part of the multifunctional protein replicase polyprotein 1ab that is involved in the transcription and replication of viral RNA. NSP1 inhibits the host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Therefore, Nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.
Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody.
抗原
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