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ZAP70 抗体 (AA 247-382)

Name: ZAP70 抗体 (AA 247-382)
SKU: ABIN7272013
Availability: OutOfStock

This 小鼠单克隆 anti-ZAP70 antibody (Clone C-D12) specifically detects ZAP70 in FACS. The antibody is reactive with 人 samples.

产品编号 ABIN7272013

发货至: 中国

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Quick Overview for ZAP70 抗体 (AA 247-382) (ABIN7272013)

抗原

See all ZAP70 抗体

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This ZAP70 antibody is un-conjugated

应用范围

Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

C-D12

Discover our top product ZAP70 Primary Antibody

抗原表位
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35

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21

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16

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1
AA 247-382

原理

ZAP-70 Unconjugated Antibody

产品特性

The clone C-D12, a mouse monoclonal antibody selectively binds with the 70kd tyrosine phosphoprotein known as ZAP-70 which is usually associated with the ζ-chain CD3-receptor-associated protein tyrosine kinase (PTK). It is a member of the Syk family that is localized exclusively to the cytosol of T cells and natural killer (NK) cells and is required for their cellular activation. It is generally considered the T-lymphocyte counterpart of Syk, a B-cell receptor (BCR)-associated kinase that belongs to the same PTK family and plays a similar role in the antigen receptor signaling in the B-lineage cells. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. ZAP-70 expression plays an important role in the clinical diagnosis of various types of hematologic malignancies.

纯化方法

Purified

纯度

>95 %

免疫原

Recombinant fragment of human ZAP70 protein (around aa 247-382)

亚型

IgG1, kappa
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (C-Term) antibody
ZAP70 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal ZAP-03 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibody
ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
ZAP70 适用: 人 IHC, FACS, ELISA, IF, StM, Coat 宿主: 小鼠 Monoclonal ZAP70-2035 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1F3G9 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 337-600) antibody
ZAP70 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody
ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-254) antibody
ZAP70 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 2F3-2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D9C2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-300) antibody
ZAP70 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) antibody
ZAP70 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C
抗原

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

别名

Zap70

基因ID

7535

UniProt

P43403

途径

TCR Signaling, Ubiquitin Proteasome Pathway