CD47 抗体
Quick Overview for CD47 抗体 (ABIN7271949)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD47 Unconjugated Antibody
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产品特性
- The clone B6H12, a mouse monoclonal antibody selectively recognizes a ~50 kDa N-linked glycan protein originally known as integrin-associated protein or IAP and currently known as CD47. CD47 is an unusual Immunoglobulin (Ig) family member, with an Ig variable-like amino-terminal extracellular domain and a five times membrane-spanning carboxyl-terminal region. It is broadly expressed on the plasma membranes of all hematopoietic cells, including erythrocytes. CD47 plays various important roles in cellular functional processes, including proliferation, apoptosis, adhesion, migration, and also in immune regulation and homeostasis. CD47 is highly expressed on myeloma cells and may be considered as a potential therapeutic candidate for myeloma therapy.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Intact CD47 purified from placenta
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- CD47
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别名
- CD47
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基因ID
- 961
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UniProt
- Q08722
抗原
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