Integrin Alpha2b 抗体 (FITC)
Quick Overview for Integrin Alpha2b 抗体 (FITC) (ABIN7271934)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD41a FITC Antibody
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产品特性
- The clone 962C1, a mouse monoclonal antibody, reacts with the human CD41 Molecule, the integrin alpha-IIb also known as platelet GPIIb. CD41 is composed of two subunits GPIIbα (120 kDa) and GPIIbβ (23 kDa) that interact with CD61 to form a functional protein receptor in the presence of calcium. This protein receptor involves in the blood coagulation system, by mediating platelet adhesion and aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins like von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocytes and platelets. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Recombinant full-length human Integrin alpha IIb protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- Integrin Alpha2b (CD41)
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别名
- CD41a
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基因ID
- 3674
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UniProt
- P08514
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途径
- Integrin Complex
抗原
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