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Recombinant SARS-CoV-2 Spike 抗体 (RBD)

This anti-SARS-CoV-2 Spike antibody is a 小鼠 单克隆 antibody detecting SARS-CoV-2 Spike in . Suitable for SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta 和 SARS CoV-2 Gamma.
产品编号 ABIN7271751
发货至: 中国

Quick Overview for Recombinant SARS-CoV-2 Spike 抗体 (RBD) (ABIN7271751)

抗原

See all SARS-CoV-2 Spike 抗体
SARS-CoV-2 Spike

抗体类型

Recombinant Antibody

适用

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SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma

宿主

  • 54
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小鼠

克隆类型

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  • 18
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单克隆

标记

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This SARS-CoV-2 Spike antibody is un-conjugated

应用范围

请咨询

质量等级

MALS verified

克隆位点

AM334
  • 抗原表位

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    RBD

    原理

    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM334) (Beta & Gamma Specific) (MALS verified)

    特异性

    This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

    产品特性

    Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.

    免疫原

    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) (ABIN7271751 and ABIN7273339) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.

    亚型

    IgG1
  • 限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -80 °C

    储存方法

    -70°C
  • 抗原

    SARS-CoV-2 Spike

    背景

    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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