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Recombinant SARS-CoV-2 Spike 抗体 (RBD) (Biotin)

Name: Recombinant SARS-CoV-2 Spike 抗体 (RBD) (Biotin)
SKU: ABIN7273331
Availability: OutOfStock

This anti-SARS-CoV-2 Spike antibody is a 小鼠 Chimeric antibody detecting SARS-CoV-2 Spike in ELISA, Neut 和 SR. Suitable for SARS Coronavirus-2 (SARS-CoV-2).

产品编号 ABIN7273331

发货至: 中国

Quick Overview for Recombinant SARS-CoV-2 Spike 抗体 (RBD) (Biotin) (ABIN7273331)

抗原

See all SARS-CoV-2 Spike 抗体

SARS-CoV-2 Spike

抗体类型

Recombinant Antibody

适用

SARS Coronavirus-2 (SARS-CoV-2)

宿主

小鼠

克隆类型

Chimeric

标记

This SARS-CoV-2 Spike antibody is conjugated to Biotin

应用范围

ELISA, Neutralization (Neut), Spike and Recovery (SR)

质量等级

MALS verified

克隆位点

AM122

Discover our top product SARS-CoV-2 Spike Primary Antibody

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RBD

原理

Biotinylated Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (MALS verified)

特异性

This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

产品特性

Recombinant Antibodies produced in HEK293. Biotinylated Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1. Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (S1N-M122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 Protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2).

免疫原

Biotinylated Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (ABIN7271742 and ABIN7273331) Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (ABIN6953206 and ABIN6953211) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 Protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2).

亚型

IgG1
anti-SARS-CoV-2 Spike (C-Term) antibody
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-SARS-CoV-2 Spike antibody
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma, SARS CoV-2 Alpha ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-SARS-CoV-2 Spike (AA 319-541) antibody
Animal-Free 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, FACS, IF 宿主: 小鼠 Monoclonal AB68-A09 unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB 宿主: Human Monoclonal AM004414 (414-4) unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Human Monoclonal AM015553 (553-15) unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (AA 319-541) antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS 宿主: 兔 Monoclonal DM54 unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (RBD) antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) WB 宿主: 山羊 Polyclonal unconjugated

anti-SARS-CoV-2 Spike antibody
Research Grade 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS 宿主: Human Monoclonal CR3022 unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (RBD) antibody
Verified 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB 宿主: 山羊 Polyclonal unconjugated

anti-SARS-CoV-2 Spike (RBD) antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS 宿主: 兔 Monoclonal DM26 unconjugated

应用备注

This antibody can be paired with other Anti-SARS-CoV-2 Spike S1 antibodies to detect SARS-CoV-2 Spike S1 protein in sandwich ELISA or LFA assay.

说明

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

限制

仅限研究用
状态

Powder

储存条件

-20 °C

储存方法

-20°C
抗原

SARS-CoV-2 Spike

背景

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.