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Recombinant SARS-CoV-2 Spike 抗体 (RBD) (PE)

This anti-SARS-CoV-2 Spike antibody is a 小鼠 Chimeric antibody detecting SARS-CoV-2 Spike in Neut 和 FACS. Suitable for SARS Coronavirus-2 (SARS-CoV-2).
产品编号 ABIN7271728
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant SARS-CoV-2 Spike 抗体 (RBD) (PE) (ABIN7271728)

抗原

See all SARS-CoV-2 Spike (SARS-CoV-2 S) 抗体
SARS-CoV-2 Spike (SARS-CoV-2 S)

抗体类型

Recombinant Antibody

适用

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SARS Coronavirus-2 (SARS-CoV-2)

宿主

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小鼠

克隆类型

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Chimeric

标记

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This SARS-CoV-2 Spike antibody is conjugated to PE

应用范围

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Neutralization (Neut), Flow Cytometry (FACS)

克隆位点

AM122
  • 抗原表位

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    RBD

    原理

    PE-Labeled Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122)

    特异性

    This product is a specific antibody specifically reacts with This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

    产品特性

    Recombinant Antibodies produced in HEK293. PE-Labeled Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 is isolated from a Spike RBD infected Mouse and is recombinantly produced from human 293 cells (HEK293)

    免疫原

    PE-Labeled Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a PE-labeled chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in ELISA, this chimeric monoclonal antibody can bind the spike protein of all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2).

    亚型

    IgG1
  • 应用备注

    Flow Cytometry (Neutralizing assay)

    Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

    限制

    仅限研究用
  • 状态

    Powder

    储存条件

    -20 °C

    储存方法

    -20°C, avoid light
  • 抗原

    SARS-CoV-2 Spike (SARS-CoV-2 S)

    别名

    SARS-CoV-2 Spike

    物质类

    Viral Protein

    背景

    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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