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Recombinant SARS-CoV-2 Nucleocapsid 抗体 (Biotin)

This anti-SARS-CoV-2 Nucleocapsid antibody is a 小鼠 Chimeric antibody detecting SARS-CoV-2 Nucleocapsid in ELISA. Suitable for SARS Coronavirus-2 (SARS-CoV-2).
产品编号 ABIN7273318
发货至: 中国

Quick Overview for Recombinant SARS-CoV-2 Nucleocapsid 抗体 (Biotin) (ABIN7273318)

抗原

See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) 抗体
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

抗体类型

Recombinant Antibody

适用

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SARS Coronavirus-2 (SARS-CoV-2)

宿主

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小鼠

克隆类型

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Chimeric

标记

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This SARS-CoV-2 Nucleocapsid antibody is conjugated to Biotin

应用范围

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ELISA

质量等级

MALS verified

克隆位点

AM223
  • 原理

    Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) (MALS verified)

    特异性

    This product can recognize SARS-CoV-2 nucleocapsid protein. No cross-reactivity is detected with nucleocapsid protein of other coronaviruses, including MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

    产品特性

    Recombinant Antibodies produced in HEK293. Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Nucleocapsid Protein. This chimeric antibody is purified by Protein A affinity chromatography.

    免疫原

    Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Nucleocapsid Protein. This chimeric antibody is purified by Protein A affinity chromatography.

    亚型

    IgG1
  • 应用备注

    This antibody can be paired with other Anti-SARS-CoV-2 Nucleocapsid antibodies to detect SARS-CoV-2 Nucleocapsid protein in sandwich ELISA or LFA assay.

    说明

    A chemically labeled biotinylated protein with ultra sensitivity.
    The product is produced using a chemical labeling approach. The primary amines in the side chains of lysine residues and the N-terminus of protein are conjugated with biotins.
    Chemical labeling usually results in multiple biotin attachment on a single protein molecule, which could potentially lead to higher detection sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -80 °C

    储存方法

    -70°C
  • 抗原

    SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

    别名

    SARS-CoV-2 Nucleocapsid protein

    背景

    Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
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