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ZNF451 抗体 (AA 600-900)

This anti-ZNF451 antibody is a 兔 多克隆 antibody detecting ZNF451 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7271489
发货至: 中国

Quick Overview for ZNF451 抗体 (AA 600-900) (ABIN7271489)

抗原

See all ZNF451 抗体
ZNF451 (Zinc Finger Protein 451 (ZNF451))

适用

  • 13
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宿主

  • 13

克隆类型

  • 13
多克隆

标记

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This ZNF451 antibody is un-conjugated

应用范围

  • 13
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 3
    • 2
    • 1
    • 1
    AA 600-900

    原理

    ZNF451 Rabbit pAb

    序列

    SSPRGKWQCR ICEDMFDSQE YVKQHCMSLA SHKFHRYSCA HCRKPFHKIE TLYRHCQDEH DNEIKIKYFC GLCDLIFNVE EAFLSHYEEH HSIDYVFVSE KTETSIKTED DFPVIETSNQ LTCGCRESYI CKVNRKEDYS RCLQIMLDKG KLWFRCSLCS ATAQNLTDMN THIHQVHKEK SDEEEQQYVI KCGTCTKAFH DPESAQQHFH RKHCFLQKPS VAHFGSEKSN LYKFTASASH TERKLKQAIN YSKSLDMEKG VENDLSYQNI EEEIVELPDL DYLRTMTHIV FVDFDNWSNF F

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ZNF451 (NP_001026794.1).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZNF451 (Zinc Finger Protein 451 (ZNF451))

    别名

    ZNF451

    背景

    E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro. Required for MCM4 sumoylation (By similarity. Has no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.,ZNF451,COASTER,dJ417I1.1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,ZNF451

    分子量

    63kDa/115kDa/121kDa

    基因ID

    26036

    UniProt

    Q9Y4E5
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