电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

VAV1 抗体 (AA 100-200)

This anti-VAV1 antibody is a 兔 多克隆 antibody detecting VAV1 in WB. Suitable for 人.
产品编号 ABIN7271302
发货至: 中国

Quick Overview for VAV1 抗体 (AA 100-200) (ABIN7271302)

抗原

See all VAV1 抗体
VAV1 (Vav 1 Oncogene (VAV1))

适用

  • 66
  • 38
  • 24
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 65
  • 4

克隆类型

  • 64
  • 5
多克隆

标记

  • 50
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This VAV1 antibody is un-conjugated

应用范围

  • 49
  • 35
  • 18
  • 9
  • 8
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 14
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-200

    原理

    VAV1 Rabbit pAb

    序列

    FDVQDFGKVI YTLSALSWTP IAQNRGIMPF PTEEESVGDE DIYSGLSDQI DDTVEEDEDL YDCVENEEAE GDEIYEDLMR SEPVSMPPKM TEYDKRCCCL R

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VAV1 (NP_005419.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    VAV1 (Vav 1 Oncogene (VAV1))

    别名

    VAV1

    背景

    This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,VAV1,VAV,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,VAV1

    分子量

    94kDa/98kDa

    基因ID

    7409

    UniProt

    P15498

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
You are here:
Chat with us!