UNC13B 抗体 (AA 1-350)
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北京 101111
Quick Overview for UNC13B 抗体 (AA 1-350) (ABIN7271215)
抗原
See all UNC13B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-350
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原理
- UNC13B Rabbit pAb
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序列
- MSLLCVRVKR AKFQGSPDKF NTYVTLKVQN VKSTTVAVRG DQPSWEQDFM FEISRLDLGL SVEVWNKGLI WDTMVGTVWI ALKTIRQSDE EGPGEWSTLE AETLMKDDEI CGTRNPTPHK ILLDTRFELP FDIPEEEARY WTYKWEQINA LGADNEYSSQ EESQRKPLPT AAAQCSFEDP DSAVDDRDSD YRSETSNSFP PPYHTASQPN ASVHQFPVPV RSPQQLLLQG SSRDSCNDSM QSYDLDYPER RAISPTSSSR YGSSCNVSQG SSQLSELDQY HEQDDDHRET DSIHSCHSSH SLSRDGQAGF GEQEKPLEVT GQAEKEAACE PKEMKEDATT HPPPDLVLQK
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human UNC13B (NP_006368.3).
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亚型
- IgG
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anti-Unc-13 Homolog B (UNC13B) (AA 12-215) antibody
UNC13B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (Internal Region) antibodyUNC13B 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (AA 1062-1091) antibodyUNC13B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22476 unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (Internal Region) antibodyVerified UNC13B 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (AA 1482-1591) antibodyUNC13B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UNC13B (Unc-13 Homolog B (UNC13B))
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别名
- UNC13B
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背景
- This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.,UNC13B,MUNC13,UNC13,Unc13h2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,UNC13B
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分子量
- 180kDa/182kDa
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基因ID
- 10497
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UniProt
- O14795
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途径
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
抗原
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