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USP18 抗体 (AA 200-300)

This anti-USP18 antibody is a 兔 多克隆 antibody detecting USP18 in WB, IF 和 IHC. Suitable for 人.
产品编号 ABIN7271145
发货至: 中国

Quick Overview for USP18 抗体 (AA 200-300) (ABIN7271145)

抗原

See all USP18 抗体
USP18 (Ubiquitin Specific Peptidase 18 (USP18))

适用

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宿主

  • 19
  • 3

克隆类型

  • 22
多克隆

标记

  • 18
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This USP18 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 7
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    • 1
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    AA 200-300

    原理

    USP18 Rabbit pAb

    序列

    DVDSKPLKTL EDALHCFFQP RELSSKSKCF CENCGKKTRG KQVLKLTHLP QTLTIHLMRF SIRNSQTRKI CHSLYFPQSL DFSQILPMKR ESCDAEEQSG G

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human USP18 (NP_059110.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    USP18 (Ubiquitin Specific Peptidase 18 (USP18))

    别名

    USP18

    背景

    The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15.,USP18,ISG43,UBP43,PTORCH2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP18

    分子量

    43kDa

    基因ID

    11274

    UniProt

    Q9UMW8
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