TPSB2 抗体
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北京 101111
Quick Overview for TPSB2 抗体 (ABIN7271017)
抗原
See all TPSB2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mast Cell Tryptase (TPSB2) Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Mast Cell Tryptase (TPSB2) (TPSB2)
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亚型
- IgG
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anti-Tryptase beta 2 (TPSB2) (AA 30-276) antibody
TPSB2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 30-274) antibodyTPSB2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 31-275) antibodyTPSB2 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 32-276) antibodyTPSB2 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 35-275) antibodyTPSB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TPSB2 (Tryptase beta 2 (TPSB2))
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别名
- TPSB2
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背景
- Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008],TPS2, tryptaseB, tryptaseC,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Ubiquitin,TPSB2
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分子量
- 30kDa
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基因ID
- 64499
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UniProt
- P20231
抗原
-
