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TRMT112 抗体 (AA 1-125)

This anti-TRMT112 antibody is a 兔 多克隆 antibody detecting TRMT112 in WB. Suitable for 人.
产品编号 ABIN7271001
发货至: 中国

Quick Overview for TRMT112 抗体 (AA 1-125) (ABIN7271001)

抗原

See all TRMT112 抗体
TRMT112 (tRNA Methyltransferase 11-2 (TRMT112))

适用

  • 20
  • 9
  • 1

宿主

  • 17
  • 3

克隆类型

  • 18
  • 2
多克隆

标记

  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TRMT112 antibody is un-conjugated

应用范围

  • 9
  • 7
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 1
    AA 1-125

    原理

    TRMT112 Rabbit pAb

    序列

    MKLLTHNLLS SHVRGVGSRG FPLRLQATEV RICPVEFNPN FVARMIPKVE WSAFLEAADN LRLIQVPKGP VEGYEENEEF LRTMHHLLLE VEVIEGTLQC PESGRMFPIS RGIPNMLLSE EETES

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human TRMT112 (NP_057488.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TRMT112 (tRNA Methyltransferase 11-2 (TRMT112))

    别名

    TRMT112

    背景

    Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7 position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.,TRMT112,HSPC152,HSPC170,TRM112,TRMT11-2,hTrm112,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,TRMT112

    分子量

    13kDa/14kDa

    基因ID

    51504

    UniProt

    Q9UI30
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