TRMT112 抗体 (AA 1-125)
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北京 101111
Quick Overview for TRMT112 抗体 (AA 1-125) (ABIN7271001)
抗原
See all TRMT112 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-125
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原理
- TRMT112 Rabbit pAb
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序列
- MKLLTHNLLS SHVRGVGSRG FPLRLQATEV RICPVEFNPN FVARMIPKVE WSAFLEAADN LRLIQVPKGP VEGYEENEEF LRTMHHLLLE VEVIEGTLQC PESGRMFPIS RGIPNMLLSE EETES
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human TRMT112 (NP_057488.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRMT112 (tRNA Methyltransferase 11-2 (TRMT112))
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别名
- TRMT112
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背景
- Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7 position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.,TRMT112,HSPC152,HSPC170,TRM112,TRMT11-2,hTrm112,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,TRMT112
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分子量
- 13kDa/14kDa
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基因ID
- 51504
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UniProt
- Q9UI30
抗原
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