TMED10 抗体 (AA 35-190)
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北京 101111
Quick Overview for TMED10 抗体 (AA 35-190) (ABIN7270945)
抗原
See all TMED10 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 35-190
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原理
- [KO Validated] TMED10 Rabbit pAb
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序列
- HLPINSRKCL REEIHKDLLV TGAYEISDQS GGAGGLRSHL KITDSAGHIL YSKEDATKGK FAFTTEDYDM FEVCFESKGT GRIPDQLVIL DMKHGVEAKN YEEIAKVEKL KPLEVELRRL EDLSESIVND FAYMKKREEE MRDTNESTNT RVLYFS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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别名
- TMED10
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背景
- This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.,TMED10,P24(DELTA),S31I125,S31III125,TMP21,Tmp-21-I,p23,p24d1,Signal Transduction,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,TMED10
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分子量
- 24kDa
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基因ID
- 10972
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UniProt
- P49755
抗原
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