TOP1MT 抗体 (AA 470-550)
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北京 101111
Quick Overview for TOP1MT 抗体 (AA 470-550) (ABIN7270851)
抗原
See all TOP1MT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-550
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原理
- TOP1MT Rabbit pAb
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序列
- RATPSTFEKS MQNLQTKIQA KKEQVAEARA ELRRARAEHK AQGDGKSRSV LEKKRRLLEK LQEQLAQLSV QATDKEENKQ V
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 470-550 of human TOP1MT (NP_443195.1).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
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别名
- TOP1MT
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背景
- This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TOP1MT,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TOP1MT
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分子量
- 58kDa/69kDa
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基因ID
- 116447
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UniProt
- Q969P6
抗原
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