电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TPMT 抗体

This anti-TPMT antibody is a 兔 单克隆 antibody detecting TPMT in WB. Suitable for 人.
产品编号 ABIN7270797
发货至: 中国

Quick Overview for TPMT 抗体 (ABIN7270797)

抗原

See all TPMT 抗体
TPMT (Thiopurine S-Methyltransferase (TPMT))

适用

  • 46
  • 13
  • 13
  • 2
  • 2

宿主

  • 36
  • 10

克隆类型

  • 33
  • 13
单克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPMT antibody is un-conjugated

应用范围

  • 35
  • 21
  • 21
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 原理

    TPMT Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of Human TPMT.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TPMT (Thiopurine S-Methyltransferase (TPMT))

    别名

    TPMT

    背景

    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT

    分子量

    28kDa

    基因ID

    7172

    UniProt

    P51580
You are here:
Chat with us!