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TGIF1 抗体 (AA 123-272)

This anti-TGIF1 antibody is a 兔 多克隆 antibody detecting TGIF1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7270795
发货至: 中国

Quick Overview for TGIF1 抗体 (AA 123-272) (ABIN7270795)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

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克隆类型

  • 33
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多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 123-272

    原理

    TGIF1 Rabbit pAb

    序列

    VESVMGIKNF MPALEETPFH SCTAGPNPTL GRPLSPKPSS PGSVLARPSV ICHTTVTALK DVPFSLCQSV GVGQNTDIQQ IAAKNFTDTS LMYPEDTCKS GPSTNTQSGL FNTPPPTPPD LNQDFSGFQL LVDVALKRAA EMELQAKLTA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 123-272 of human TGIF1 (NP_003235.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.,TGIF1,HPE4,TGIF,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,Embryonic Stem Cells,Neural Stem Cells,Target gene,TGIF1

    基因ID

    7050

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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