TTC3 抗体 (AA 1400-1700)
This anti-TTC3 antibody is a 兔 多克隆 antibody detecting TTC3 in WB. Suitable for 人.
1 image
Quick Overview for TTC3 抗体 (AA 1400-1700) (ABIN7270791)
抗原
See all TTC3 抗体
TTC3
(Tetratricopeptide Repeat Domain 3 (TTC3))
适用
人
宿主
兔
克隆类型
多克隆
标记
This TTC3 antibody is un-conjugated
应用范围
Western Blotting (WB)
-
-
抗原表位
- AA 1400-1700
-
原理
- TTC3 Rabbit pAb
-
序列
- IASETQILEG SLGISVKSHC STGDAHTVLS ESNRNDEHCG NSNNKCEVIP ESTSAVTNIP HVQMVAIQVS WNIIHQEVNT EPYNPFEERQ GEISRIEKEH QVLQDQLQEV YENYEQIKLK GLEETRDLEE KLKRHLEENK ISKTELDWFL QDLEREIKKW QQEKKEIQER LKSLKKKIKK VSNASEMYTQ KNDGKEKEHE LHLDQSLEIS NTLTNEKMKI EEYIKKGKED YEESHQRAVA AEVSVLENWK ESEVYKLQIM ESQAEAFLKK LGLISRDPAA YPDMESDIRS WELFLSNVTK E
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human TTC3 (NP_003307.3).
-
亚型
- IgG
-
-
anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibody
TTC3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibodyTTC3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
-
别名
- TTC3
-
背景
- E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3 in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation.,TTC3,DCRR1,RNF105,TPRDIII,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,TTC3
-
分子量
- 194kDa/203kDa/229kDa
-
基因ID
- 7267
-
UniProt
- P53804
抗原
-
You are here:
