TBC1D5 抗体 (AA 446-795)
This anti-TBC1D5 antibody is a 兔 多克隆 antibody detecting TBC1D5 in WB. Suitable for 人.
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Quick Overview for TBC1D5 抗体 (AA 446-795) (ABIN7270750)
抗原
See all TBC1D5 抗体
TBC1D5
(TBC1 Domain Family, Member 5 (TBC1D5))
适用
人
宿主
兔
克隆类型
多克隆
标记
This TBC1D5 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 446-795
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原理
- TBC1D5 Rabbit pAb
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序列
- NAKGAPLNIN KVSNSLINFG RKLISPAMAP GSAGGPVPGG NSSSSSSVVI PTRTSAEAPS HHLQQQQQQQ RLMKSESMPV QLNKGLSSKN ISSSPSVESL PGGREFTGSP PSSATKKDSF FSNISRSRSH SKTMGRKESE EELEAQISFL QGQLNDLDAM CKYCAKVMDT HLVNIQDVIL QENLEKEDQI LVSLAGLKQI KDILKGSLRF NQSQLEAEEN EQITIADNHY CSSGQGQGRG QGQSVQMSGA IKQASSETPG CTDRGNSDDF ILISKDDDGS SARGSFSGQA QPLRTLRSTS GKSQAPVCSP LVFSDPLMGP ASASSSNPSS SPDDDSSKDS GFTIVSPLDI
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 446-795 of human TBC1D5 (NP_055559.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
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别名
- TBC1D5
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背景
- May act as a GTPase-activating protein (GAP for Rab family protein(s. May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN, the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes.,TBC1D5,TBC1D5
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分子量
- 89kDa/91kDa
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基因ID
- 9779
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UniProt
- Q92609
抗原
-
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