TAX1BP3 抗体
Quick Overview for TAX1BP3 抗体 (ABIN7270742)
抗原
See all TAX1BP3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TAX1BP3 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human TAX1BP3
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亚型
- IgG
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anti-Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3) (AA 1-124) antibody
TAX1BP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3) (AA 1-124) antibodyTAX1BP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3) (AA 71-103) antibodyTAX1BP3 适用: 人 WB 宿主: 兔 Polyclonal RB54863 unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
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别名
- TAX1BP3
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背景
- This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,TIP-1, TIP1,Epigenetics & Nuclear Signaling,G protein signaling,G protein signaling_Small G proteins,Signal Transduction,Stem Cells,TAX1BP3
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分子量
- 14kDa
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基因ID
- 30851
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UniProt
- O14907
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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