SYNGAP1 抗体
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北京 101111
Quick Overview for SYNGAP1 抗体 (ABIN7270663)
抗原
See all SYNGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SynGAP Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human SynGAP
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亚型
- IgG
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anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 1161-1343) antibody
SYNGAP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 1169-1183) antibodyVerified SYNGAP1 适用: 人, 小鼠 WB, ELISA, IF, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 60-72) antibodyVerified SYNGAP1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (C-Term) antibodySYNGAP1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 1185-1199) antibodySYNGAP1 适用: 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
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别名
- SYNGAP1
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背景
- This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016],MRD5, RASA1, RASA5, SYNGAP,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Neuroscience,Signal Transduction,SYNGAP1
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分子量
- 147kDa
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基因ID
- 8831
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UniProt
- Q96PV0
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途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
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