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SOCS2 抗体

This anti-SOCS2 antibody is a 兔 单克隆 antibody detecting SOCS2 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7270641
发货至: 中国

Quick Overview for SOCS2 抗体 (ABIN7270641)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

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宿主

  • 46
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克隆类型

  • 38
  • 12
单克隆

标记

  • 29
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This SOCS2 antibody is un-conjugated

应用范围

  • 24
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    SOCS2 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human SOCS2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    SOCS2

    背景

    This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2,Apoptosis,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Neuroscience,Signal Transduction,SOCS2

    分子量

    22kDa

    基因ID

    8835

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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