SPRY3 抗体 (C-Term)
Quick Overview for SPRY3 抗体 (C-Term) (ABIN7270556)
抗原
See all SPRY3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SPRY3 Rabbit pAb
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序列
- TDDEDNCADE PCSCGPSSCF VRWAAMSLIS LFLPCLCCYL PTRGCLHLCQ QGYDSLRRPG CRCKRHTNTV CRKISSGSAP FPKAQEKSV
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human SPRY3 (NP_005831.1).
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亚型
- IgG
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anti-Sprouty Homolog 3 (SPRY3) (AA 91-288) antibody
SPRY3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 261-288), (C-Term) antibodySPRY3 适用: 人 WB 宿主: 兔 Polyclonal RB32263 unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 38-87) antibodySPRY3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 71-120) antibodySPRY3 适用: 人, 小鼠, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 91-288) antibodySPRY3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 88-281) antibodySPRY3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SPRY3 (Sprouty Homolog 3 (SPRY3))
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别名
- SPRY3
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背景
- Members of the Sprouty family (Sprouty 1-4) are inducible negative regulators of growth factors that act through tyrosine kinase receptors. Mammalian Sprouty homologs share a well-conserved cysteine-rich carboxy-terminal domain with their Drosophila counterparts. Sprouty proteins are cytoplasmic in unstimulated cells, but in cells stimulated by growth factors they anchor to the plasma membrane by palmitoylation. Sprouty 1 and 2 associate with caveolin-1 in perinuclear and vesicular structures and are phosphorylated on serine residues. Sprouty 2 can associate with c-Cbl, a downregulator of RTK signaling, and inhibit the activities of several growth factors. Unlike the widely expressed Sprouty members 1, 2 and 4, Sprouty 3 expression is restricted to adult brain and testis. Sprouty 4 is a target of the WNT/b-catenin signaling pathway in progenitor cells. In conclusion, members of Sprouty inhibit FGF and VEGF-mediated cell proliferation, suggesting that they may regulate angiogenesis in normal and disease processes.,SPRY3,spry-3,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,SPRY3
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分子量
- 31kDa
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基因ID
- 10251
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UniProt
- O43610
抗原
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