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SPRY2 抗体 (AA 1-100)

This anti-SPRY2 antibody is a 兔 多克隆 antibody detecting SPRY2 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7270555
发货至: 中国

Quick Overview for SPRY2 抗体 (AA 1-100) (ABIN7270555)

抗原

See all SPRY2 抗体
SPRY2 (Sprouty Homolog 2 (SPRY2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPRY2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-100

    原理

    SPRY2 Rabbit pAb

    序列

    MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR NTNEYTEGPT VVPRPGLKPA PRPSTQHKHE RLHGLPEHRQ PPRLQHSQVH

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SPRY2 (NP_005833.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SPRY2 (Sprouty Homolog 2 (SPRY2))

    别名

    SPRY2

    背景

    This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.,SPRY2,IGAN3,hSPRY2,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Neuroscience,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,SPRY2

    分子量

    34kDa

    基因ID

    10253

    UniProt

    O43597

    途径

    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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