SNW1 抗体 (AA 300-536)
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北京 101111
Quick Overview for SNW1 抗体 (AA 300-536) (ABIN7270386)
抗原
See all SNW1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-536
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原理
- SNW1 Rabbit pAb
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序列
- EAVEMRAQVE RKMAQKEKEK HEEKLREMAQ KARERRAGIK THVEKEDGEA RERDEIRHDR RKERQHDRNL SRAAPDKRSK LQRNENRDIS EVIALGVPNP RTSNEVQYDQ RLFNQSKGMD SGFAGGEDEI YNVYDQAWRG GKDMAQSIYR PSKNLDKDMY GDDLEARIKT NRFVPDKEFS GSDRRQRGRE GPVQFEEDPF GLDKFLEEAK QHGGSKRPSD SSRPKEHEHE GKKRRKE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 300-536 of human SNW1 (NP_036377.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SNW1 (SNW Domain Containing 1 (SNW1))
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别名
- SNW1
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背景
- This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.,SNW1,Bx42,NCOA-62,PRPF45,Prp45,SKIIP,SKIP,FUN20,SKIP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,SNW1
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分子量
- 61kDa
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基因ID
- 22938
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UniProt
- Q13573
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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