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TNNI1 抗体

This anti-TNNI1 antibody is a 兔 单克隆 antibody detecting TNNI1 in WB. Suitable for 人.
产品编号 ABIN7270338
发货至: 中国

Quick Overview for TNNI1 抗体 (ABIN7270338)

抗原

See all TNNI1 抗体
TNNI1 (Slow Skeletal Troponin I (TNNI1))

适用

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宿主

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克隆类型

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单克隆

标记

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This TNNI1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Troponin I1/TnI1 Rabbit mAb

    交叉反应

    人, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Troponin I1/TnI1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TNNI1 (Slow Skeletal Troponin I (TNNI1))

    别名

    TNNI1

    背景

    Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008],SSTNI, TNN1,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,TNNI1

    分子量

    22kDa

    基因ID

    7135

    UniProt

    P19237
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