SHANK2 抗体
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北京 101111
Quick Overview for SHANK2 抗体 (ABIN7270275)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SHANK2 Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human SHANK2.
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- SHANK2
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背景
- This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],AUTS17,CORTBP1,CTTNBP1,ProSAP1,SHANK,SPANK-3,SHANK2,Neuroscience,SHANK2
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基因ID
- 22941
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UniProt
- Q9UPX8
抗原
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