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SESN1 抗体

This anti-SESN1 antibody is a 兔 单克隆 antibody detecting SESN1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7270259
发货至: 中国

Quick Overview for SESN1 抗体 (ABIN7270259)

抗原

See all SESN1 抗体
SESN1 (Sestrin 1 (SESN1))

适用

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宿主

  • 52
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克隆类型

  • 54
  • 1
单克隆

标记

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  • 1
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This SESN1 antibody is un-conjugated

应用范围

  • 45
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    sestrin 1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human sestrin 1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SESN1 (Sestrin 1 (SESN1))

    别名

    SESN1

    背景

    This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],PA26, SEST1,AMPK Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,SESN1

    分子量

    70kDa

    基因ID

    27244

    UniProt

    Q9Y6P5
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