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SAFB 抗体 (AA 300-400)

This anti-SAFB antibody (ABIN7270155) is a Rabbit Polyclonal antibody detecting SAFB in WB, IF. Suitable for Human.
产品编号 ABIN7270155
发货至: 中国

Quick Overview for SAFB 抗体 (AA 300-400) (ABIN7270155)

抗原

See all SAFB 抗体
SAFB (Scaffold Attachment Factor B (SAFB))

适用

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宿主

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克隆类型

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多克隆

标记

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This SAFB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 300-400

    原理

    SAFB Rabbit pAb

    序列

    QPGDGERTDC EPVGLEPAVE QSSAASELAE ASSEELAEAP TEAPSPEARD SKEDGRKFDF DACNEVPPAP KESSTSEGAD QKMSSPEDDS DTKRLSKEEK G

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 300-400 of human SAFB (NP_002958.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SAFB (Scaffold Attachment Factor B (SAFB))

    别名

    SAFB

    背景

    This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.,SAFB,HAP,HET,SAB-B1,SAF-B,SAF-B1,SAFB1,Epigenetics & Nuclear Signaling,RNA Binding,SAFB

    分子量

    95kDa/102kDa

    基因ID

    6294

    UniProt

    Q15424

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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