RBM25 抗体 (AA 614-843)
This 兔 多克隆 anti-RBM25 antibody specifically detects RBM25 in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7270082
发货至:
中国
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Contact Info
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北京 101111
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Quick Overview for RBM25 抗体 (AA 614-843) (ABIN7270082)
抗原
See all RBM25 抗体
RBM25
(RNA Binding Motif Protein 25 (RBM25))
适用
人
宿主
兔
克隆类型
多克隆
标记
This RBM25 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- AA 614-843
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原理
- RBM25 Rabbit pAb
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序列
- KPTLRPISSA PSVSSASGNA TPNTPGDESP CGIIIPHENS PDQQQPEEHR PKIGLSLKLG ASNSPGQPNS VKRKKLPVDS VFNKFEDEDS DDVPRKRKLV PLDYGEDDKN ATKGTVNTEE KRKHIKSLIE KIPTAKPELF AYPLDWSIVD SILMERRIRP WINKKIIEYI GEEEATLVDF VCSKVMAHSS PQSILDDVAM VLDEEAEVFI VKMWRLLIYE TEAKKIGLVK
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 614-843 of human RBM25 (NP_067062.1).
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亚型
- IgG
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anti-RNA Binding Motif Protein 25 (RBM25) (AA 285-334) antibody
RBM25 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:200 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RBM25 (RNA Binding Motif Protein 25 (RBM25))
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别名
- RBM25
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背景
- RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.,RBM25,NET52,RED120,RNPC7,S164,Snu71,fSAP94,Epigenetics & Nuclear Signaling,RNA Binding,RBM25
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分子量
- 17kDa/32kDa/33kDa/100kDa
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基因ID
- 58517
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UniProt
- P49756
抗原
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