RHBDD1 抗体 (AA 206-315)
This anti-RHBDD1 antibody is a 兔 多克隆 antibody detecting RHBDD1 in WB 和 IF. Suitable for 人.
Quick Overview for RHBDD1 抗体 (AA 206-315) (ABIN7269978)
抗原
See all RHBDD1 抗体
RHBDD1
(Rhomboid Domain Containing 1 (RHBDD1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This RHBDD1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- AA 206-315
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原理
- RHBDD1 Rabbit pAb
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序列
- TQGPLKKIME ACAGGFSSSV GYPGRQYYFN SSGSSGYQDY YPHGRPDHYE EAPRNYDTYT AGLSEEEQLE RALQASLWDR GNTRNSPPPY GFHLSPEEMR RQRLHRFDSQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 206-315 of human RHBDD1 (NP_115652.2).
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亚型
- IgG
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anti-Rhomboid Domain Containing 1 (RHBDD1) antibody
RHBDD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 1 (RHBDD1) (C-Term) antibodyRHBDD1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
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别名
- RHBDD1
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背景
- Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.,RHBDD1,RRP4,Cell Biology & Developmental Biology,Apoptosis,RHBDD1
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分子量
- 12kDa/35kDa
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基因ID
- 84236
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UniProt
- Q8TEB9
抗原
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