ARHGAP11B 抗体 (AA 218-267)
This 兔 多克隆 anti-ARHGAP11B antibody specifically detects ARHGAP11B in WB. The antibody is reactive with 人 samples.
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产品编号 ABIN7269963
发货至:
中国
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Quick Overview for ARHGAP11B 抗体 (AA 218-267) (ABIN7269963)
抗原
ARHGAP11B
(rho GTPase Activating Protein 11B (ARHGAP11B))
适用
人
宿主
兔
克隆类型
多克隆
标记
This ARHGAP11B antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 218-267
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原理
- ARHGAP11B Rabbit pAb
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序列
- EKKGVYQTLS WKRYQPCWVL MVSVLLHHWK ALKKVNMKLL VNIREREDNV
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 218-267 of human ARHGAP11B (NP_001034930.1).
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亚型
- IgG
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anti-rho GTPase Activating Protein 11B (ARHGAP11B) (C-Term) antibody
ARHGAP11B 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ARHGAP11B (rho GTPase Activating Protein 11B (ARHGAP11B))
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别名
- ARHGAP11B
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背景
- Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis, thereby playing a key role in neocortex expansion. Promotes the proliferation of basal progenitors by inhibiting the mitochondrial permeability transition pore (mPTP: delays the opening of the mPTP via interaction with ADP:ATP translocase, thereby increasing mitochondrial Ca(2+ concentration and inducing glutamine catabolism, which is required for basal progenitor proliferation. Does not possess GTPase activator activity: the absence of GTPase activator activity is required to promote amplification of basal progenitors during neocortex development.,ARHGAP11B,FAM7B1,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP11B
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分子量
- 30kDa
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基因ID
- 89839
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UniProt
- Q3KRB8
抗原
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