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p107 抗体 (AA 100-200)

This anti-p107 antibody is a 兔 多克隆 antibody detecting p107 in WB. Suitable for 人.
产品编号 ABIN7269942
发货至: 中国

Quick Overview for p107 抗体 (AA 100-200) (ABIN7269942)

抗原

See all p107 (RBL1) 抗体
p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This p107 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 100-200

    原理

    RBL1 Rabbit pAb

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RBL1 (NP_002886.2).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

    别名

    RBL1

    背景

    The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.,PRB1, p107, CP107,RBL1

    分子量

    120kDa

    基因ID

    5933

    UniProt

    P28749

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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